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Okamura-Oho Yuko
Department of Food and Health Sciences
Professor
Last Updated :2025/05/20

Researcher Profile and Settings

Name

  • Name

    Okamura-Oho Yuko

Education, Etc.

  • University of Tokyo, Faculty of Medicine, Medicine
  • Research Institute, Hospital for Sick Children,Toronto, Canada

Degree

  • M.D., Ph.D.

Job

  • National Research Institute for Child Health and Development, Department of Genetics, Researcher
  • RIKEN, Researcher, Team leader

Researcher Profile and Settings

Published Papers

  • ViBrism DB: an interactive search and viewer platform for 2D/3D anatomical images of gene expression and co-expression networks, Oct. 2018, Nucleic Acids Research, gky951
  • Anatomical landmarks for registration of experimental image data to volumetric rodent brain atlasing templates　, Apr. 2015, J. Neurosci. Methods, 240, 161 - 169
  • Integration of Expression Maps and Co-Expression Networks Compassing Novel Gene Functions in the Brain, Apr. 2014, Sci. Rep., 4, 6969
  • Transcriptome Tomography for Brain Analysis in the Web-Accessible Anatomical Space　, Apr. 2012, PLOS ONE, 7, 9, 45373
  • Y LRRN4 and UPK3B are markers of primary mesothelial cells, Apr. 2011, PLoS ONE, 6, 10, 25391
  • Expression analysis for inverted effects of serotonin transporter inactivation, Apr. 2008, Biochem.Biophys.Res.Commun., 368, 43 - 49
  • Time-of-flight detection of monoatomic ions generated 3 by femtosecond laser ablation from large molecules, Apr. 2008, Nucl. Instr. and Meth. B, 266, 992 - 997
  • Large-scale clustering of CAGE tag expression data, Apr. 2007, BMC. Bioinformatics., 8, 161
  • Naturally occurring antisense RNA of histone H2a in mouse cultured cell lines, Apr. 2005, BMC. Genet., 6, 23
  • The transcriptional landscape of the mammalian genome, Apr. 2005, Science, 309, 1559 - 1563
  • Expression analysis of genes responsible for serotonin signaling in the brain, Apr. 2005, Neurobiol. Dis., 19, 378 - 385
  • Dentatorubral-pallidoluysian atrophy protein is phosphorylated by c-Jun NH2-terminal kinase, Apr. 2003, Hum. Mol. Genet., 12, 1535 - 1542
  • Genomic structure and alternative splicing of the insulin receptor tyrosine kinase substrate of 53-kDa protein, Apr. 2003, J. Hum. Genet., 48, 410 - 414
  • Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates, Apr. 2001, Cell Death. Differ., 8, 377 - 386
  • Distinctive tissue distribution and phosphorylation of IRSp53 isoforms, Apr. 2001, Biochem. Biophys. Res. Commun., 289, 957 - 960
  • Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosis, Apr. 2000, Biochem J., 348, 621 - 632
  • Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine, Apr. 2000, Hum. Mol. Genet., 9, 1433 - 1442
  • Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate, Apr. 1999, Hum. Mol. Genet., 8, 947 - 957
  • DRPLA遺伝子産物と相互作用する蛋白遺伝子のクローニング, Apr. 1999, 日本臨床, 57, 856 - 861
  • 歯状核赤核淡蒼球ルイ体委縮症責任遺伝子産物（DRPLAタンパク）に結合する蛋白の解析, Apr. 1999, 東京大学
  • Expression of extended polyglutamine sequentially activates initiator and effector caspases, Apr. 1999, Biochem. Biophys. Res. Commun., 257, 724 - 730
  • Intracellular aggregate formation of dentatorubral-pallidoluysian atrophy (DRPLA) protein with the extended polyglutamine, Apr. 1998, Biochem. Biophys. Res. Commun., 249, 96 - 102
  • Dentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosis, Apr. 1997, J. Biol. Chem., 272, 29238 - 29242
  • Maturation and degradation of beta-galactosidase in the post-Golgi compartment are regulated by cathepsin B and a non-cysteine protease, Apr. 1997, FEBS Lett., 419, 231 - 234
  • Early proteolytic cleavage with loss of a C-terminal fragment underlies altered processing of the beta-galactosidase precursor in galactosialidosis, Apr. 1996, Biochem. J., 313 ( Pt 3), 787 - 794
  • Kinetic mechanism and characterization of human beta-galactosidase precursor secreted by permanently transfected Chinese hamster ovary cells, Apr. 1994, Biochem. J., 304 ( Pt 1), 281 - 288
  • The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase, Apr. 1993, J. Clin. Invest, 91, 1198 - 1205
  • Wilsm腫瘍を合併したLeber先天盲の１例, Apr. 1990, 小児科診療, 53, 2971 - 2975
  • Fanconi症候群を伴ったミトコンドリアミオパチー（cytochrome c oxidase 部分欠損）の幼児例, Apr. 1989, 日本小児科学会雑誌, 93, 1337 - 1342
  • Clinical and genetic heterogeneity in galactosialidosis, Apr. 1988, Brain Dysfunc, 1, 285 - 293
  • 低カリウム性周期性四肢麻痺、近位筋力低下を呈し、核崩壊を主病変とする筋原性変化を認めた１小児例, Apr. 1987, 脳と発達, 19, 519 - 521
  • Muscle involvement in pyruvate dehydrogenase complex (PDHC) deficiency, Apr. 1987, Brain Dev, 9, 9 - 15
  • DNA分析によりワクチン株ウイルスを証明し得た神経芽細胞腫患児のワクチン後水痘例, Apr. 1987, 日本小児科学会雑誌, 91, 2871 - 2877
  • Case report of a girl with pyruvate decarboxylase deficiency presented with infantile spasms, Apr. 1985, Brain Dev, 7, 229
  • A scoring system for the diagnosis of lysosomal storage diseases: A preliminary study on the basis of 100 cases, Apr. 1985, Acta Paediatr Jpn, 27, 602 - 607
  • 哺乳障害、点頭てんかんで発症したpyruvate　dehydrogenase complex 欠損症の１例, Apr. 1985, 小児科診療, 49, 2134 - 2139
  • 13C標識trioctanoin負荷による小児脂肪代謝の評価, Apr. 1985, 小児科診療, 49, 2125 - 2127
  • A simple enzymatic determination of urinary sialic acid--its significance in the diagnosis of disorders of sialic acid metabolism, Apr. 1984, Clin. Chim. Acta, 144, 263 - 267
  • Galactosialidosis (b-galactosidase-neuraminidase deficiency): A new hereditary metabolic disease with abnormal degradation of enzyme molecules, Apr. 1983, Acta Paediatr Jpn, 25, 31 - 37
  • 尿中総シアル酸測定?小児における変動を中心に?, Apr. 1983, 臨床病理, 54, 165 - 168
  • ViBrism DB: an interactive search and viewer platform for 2D/3D anatomical images of gene expression and co-expression networks, 2018, Morita M, Shimokawa K, Nishimura M, Nakamura S, Tsujimura Y, Takemoto S, Tawara T, Yokota H, Wemler S, Miyamoto D, Ikeno H, Sato A, Furuichi T, Kobayashi N, Okumura Y, Yamaguchi Y, Okamura-Oho Y, Nucleic Acids Research, gky951
  • Anatomical landmarks for registration of experimental image data to volumetric rodent brain atlasing templates, 2015, Sergejeva, M, Papp, E. A., Bakker, R., Gaudnek, M. A., Okamura-Oho, Y., Boline, J., Bjaalie, J. G., J. Neurosci. Methods, 240, 161 - 169
  • Broad integration of expression maps and co-expression networks compassing novel gene functions in the brain., Nov. 2014, Okamura-Oho Y, Shimokawa K, Nishimura M, Takemoto S, Sato A, Furuichi T, Yokota H, Scientific reports, 4, 6969
  • Transcriptome tomography for brain analysis in the web-accessible anatomical space., 2012, Okamura-Oho Y, Shimokawa K, Takemoto S, Hirakiyama A, Nakamura S, Tsujimura Y, Nishimura M, Kasukawa T, Masumoto KH, Nikaido I, Shigeyoshi Y, Ueda HR, Song G, Gee J, Himeno R, Yokota H, PLoS One, 7, e45373
  • LRRN4 and UPK3B are markers of primary mesothelial cells., 2011, Kanamori-Katayama M, Kaiho A, Ishizu Y, Okamura-Oho Y, Hino O, Abe M, Kishimoto T, Sekihara H, Nakamura Y, Suzuki H, Forrest AR, Hayashizaki Y, PloS one, 6, e25391
  • 定量的3次元遺伝子発現データに基づいたマウス脳アトラスの作成とその解析, 2010, 於保祐子, 竹本智子, 横田秀夫, 生化学, 1P-0873
  • Expression analysis for inverted effects of serotonin transporter inactivation., Mar. 2008, Ichikawa M, Okamura-Oho Y, Shimokawa K, Kondo S, Nakamura S, Yokota H, Himeno R, Lesch KP, Hayashizaki Y, Biochem. Biophys. Res. Commun., 368, 1, 43 - 49
  • 3D‐ISM を用いた遺伝子発現の仮想ボクセル解析, 2008, 於保祐子, 下川和郎, 中村佐紀子, 姫野龍太郎, 横田秀夫, 生化学, 1P-0988
  • Time-of-flight detection of monoatomic ions generated 3 by femtosecond laser ablation from large molecules, 2008, Kato,T., Kobayashi,T., Kurata-Nishimura,M., Okamura-Oho,Y., Sano,T., Oyama,R., Matsumura,Y., Yamamoto,H., Hayashizaki,Y., MatsuoY., Kawai,J., Nucl. Instr. and Meth. B, 266, 6, 992 - 997
  • Large-scale clustering of CAGE tag expression data., May 2007, Shimokawa K, Okamura-Oho Y, Kurita T, Frith MC, Kawai J, Carninci P, Hayashizaki Y, BMC bioinformatics, 8, 161
  • The transcriptional landscape of the mammalian genome, 2005, Carninci,P., Kasukawa,T., ..., 188 et al, ..., Okamura-Oho,Y., Suzuki,H., Kawai,J., Hayashizaki,Y., Science, 309, 5740, 1559 - 1563
  • Expression analysis of genes responsible for serotonin signaling in the brain., Aug. 2005, Ichikawa M, Okamura-Oho Y, Okunishi R, Kanamori M, Suzuki H, Ritani A, Nitta H, Eguchi N, Urade Y, Hayashizaki Y, Neurobiology of Disease, 19, 378 - 385
  • Naturally occurring antisense RNA of histone H2a in mouse cultured cell lines., May 2005, Nishida H, Tomaru Y, Oho Y, Hayashizaki Y, BMC genetics, 6, 23
  • Dentatorubral-pallidoluysian atrophy protein is phosphorylated by c-Jun NH2-terminal kinase., Jul. 2003, Okamura-Oho Y, Miyashita T, Nagao K, Shima S, Ogata Y, Katada T, Nishina H, Yamada M, Hum. Mol. Genet. , 12, 1535 - 1542
  • Genomic structure and alternative splicing of the insulin receptor tyrosine kinase substrate of 53-kDa protein., 2003, Miyahara A, Okamura-Oho Y, Miyashita T, Hoshika A, Yamada M, J. Hum. Genet. , 48, 8, 410 - 414
  • Distinctive tissue distribution and phosphorylation of IRSp53 isoforms, 2001, Okamura-Oho,Y., Miyashita,T., & Yamada,M, Biochem. Biophys. Res. Commun., 289, 5, 957 - 960
  • Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates, 2001, U M, Miyashita T, Ohtsuka Y, Okamura-Oho Y, Shikama Y, & Yamada M., Cell Death. Differ., 8, 377 - 386
  • Protein binding of a DRPLA family through arginine-glutamic 　　　　　　　　acid dipeptide repeats is enhanced by extended polyglutamine, 2000, Yanagisawa H, Bundo M, Miyashita T, Okamura-Oho Y, Tadokoro K, Tokunaga K, Yamada M., Hum. Mol. Genet. , 9, 1433 - 1442
  • Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1　gangliosidosis, 2000, Zhang S, Bagshaw R, Hilson W, Oho Y, Hinek A, Clarke JT, & Callahan JW., Biochem J., 348, 3, 621 - 632
  • Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine withthe SH3 domain of an insulin receptor tyrosinekinase substrate. , 1999, Okamura-Oho Y, Miyashita T, Ohmi K, Yamada M., Hum Mol Genet., 8, 947 - 957
  • 1999, 57, 856 - 861
  • Expression of extended polyglutamine sequentially activates initiator and effector caspases, 1999, Miyashita T, Matsui J, Ohtsuka Y, Mami U, Fujishima S, Okamura-Oho Y, Inoue T, Yamada M, Biochem. Biophys. Res. Commun., 257, 3, 724 - 730
  • Intracellular aggregate formation of dentatorubral-pallidoluysian atrophy (DRPLA) protein with the extended polyglutamine, 1998, Miyashita T, Nagao K, Ohmi K, Yanagisawa H, Okamura-Oho Y, & Yamada M., Biochem. Biophys. Res. Commun. , 249, 1, 96 - 102
  • Maturation and degradation of beta-galactosidase in the post-Golgi compartment are regulated by cathepsin B and a non-cysteine protease. , 1997, Okamura-Oho Y, Zhang S, Callahan JW, Murata M, Oshima A, Suzuki Y., FEBS Lett., 419, 2/3, 231 - 234
  • Dentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3during apoptosis., 1997, Miyashita T,Okamura-Oho Y, Mito Y, Nagafuchi S, Yamada M., J Biol Chem., 272, 46, 29238 - 29242
  • Early proteolytic cleavage with loss of a C-terminal fragment underlies altered processing of the beta-galactosidase precursor in galactosialidosis., 1996, Okamura-Oho,Y., Zhang,S., Hilson,W., Hinek,A., & Callahan,J.W., Biochem. J. , 313, 787 - 794
  • Kinetic mechanism and characterization of human beta-galactosidase precursor secreted by permanently transfected Chinese hamster ovary cells., 1994, 21. Zhang S, McCarter JD, Okamura-Oho Y, Yaghi F, Hinek A, Withers SG, Callahan JW., Biochem J., 304, 281 - 288
  • The 67-kD elastin/laminin-binding protein is related to an enzymaticallyinactive, alternatively spliced form ofbeta-galactosidase., 1993, Hinek A, Rabinovitch M, Keeley F, Okamura-Oho Y, Callahan J., J Clin Invest., 91, 1198 - 1205
  • A infantile case of mitochondria myopathy(focal cytochrime c oxidase deficiency)., Jun. 1989, OHO YUKO, OHGA KAZUHIRO, WATANABE SABURO, IGARASHI TAKASHI, AKAGI KUNIHIKO, KOGA YASUTOSHI, NONAKA IKUYA, 日本小児科学会雑誌, 93, 6, 1337-1342
  • Diagnosis of streptococcal pharyngitis with antigen detection test for group A streptococci., Mar. 1988, OGA KAZUHIRO, MAKITA RYUJI, MAKITA JUNKO, OHO SHIN'ICHI, OHO YUKO, MIYAMA NORIKO, WATANABE SABURO, YAGINUMA SHIGERU, MINAMITANI MIKIO, 小児科診療, 51, 3, 433-437
  • Clinical and genetic heterogeneity in galactosialidosis., 1988, Suzuki Y, Nanba E, Tsuji A, Yang RC, Okamura-Oho Y, Yamanaka T., Brain Dysfunc., 1, 285 - 293
  • A hypotonic patient with hypokalemic periodic paralysis and myopathic pathology associated with nucleolysis., Nov. 1987, OHO YUKO, SUZUKI YOSHIYUKI, NONAKA IKUYA, 脳と発達, 19, 6, 519 - 521
  • Post-vaccinated varicella identified as the Oka strain with restrictive endonuclease analysis in a patient with neuroblastoma., Aug. 1987, OHO YUKO, OHGA KAZUHIRO, WATANABE SABURO, BESSHO FUMIO, YAMAMOTO ATSUKO, MINAMITANI MIKIO, TAKAHASHI MICHIAKI, 日本小児科学会雑誌, 91, 8, 2871-2877
  • Muscle involvement in pyruvate dehydrogenase complex (PDHC) deficiency., 1987, Chung SJ, Asoh S, Yamanaka T, Okamura-Oho Y, Toshima K, Woo M, Nonaka I., Brain Dev., 9, 1, 9 - 15
  • Improvements in endocrine and metabolic disturbances care. Evaluation of fat metabolism in children by oral 13C-trioctanoin loading., Nov. 1986, OHO YUKO, YAMANAKA TATSUHIRO, SUZUKI YOSHIYUKI, SUEHIRO MAKIKO, IIO MASAHIRO, 小児科診療, 49, 11, 2125-2127
  • Case report of a girl with pyruvate decarboxylase deficiency presented with infantile spasms. , 1985, Okamura Y, Saito S, Nagata E, Hakamada S, Nomura Y, Segawa M, Yamanaka T, Hosaka A., Brain Dev., 7, 229
  • A scoring system for the diagnosis of lysosomal storage diseases: A preliminary study on the basis of 100 cases., 1985, Okamura-Oho Y, Yamanaka T, Suzuki Y., Acta Paediatr Jpn.,, 27, 602 - 607
  • A simple enzymatic determination of urinary sialic acid--its significance in the diagnosis of disorders of sialic acid metabolism., 1984, Okamura-Oho,Y., Yamanaka,T., Suzuki,Y., Akagi,M., Kobayashi,T., Clin. Chim. Acta , 144, 263 - 267
  • 1983, 54, 165 - 168
  • Galactosialidosis (b-galactosidase-neuraminidase deficiency): A new hereditary metabolic disease with abnormal degradation of enzyme molecules. , 1983, Suzuki Y, Sakuraba H, Yamanaka T, Ko YM, Okamura Y. , Acta Paediatr Jpn.,, 25, 31 - 37

Published Book

  • 単行本「遺伝子のすばらしい計画」翻訳 （原著Dr Fran Balkwill), Jan. 2014, 電子書店BReNt-Books (電子書店モール「WOOK（ウック）」内)
  • 単行本「DNA はここだよ　いつもいっしょ」翻訳　（原著Dr Fran Balkwill)　, Sep. 2013, 電子書店BReNt-Books (電子書店モール「WOOK（ウック）」内)
  • 別冊 日本臨床 領域別症候群シリーズ No. 33 先天異常症候群辞典, Apr. 2001, 日本臨床社, 540 - 542
  • 別冊 日本臨床 領域別症候群シリーズ No. 34 先天異常症候群辞典, Apr. 2001, 日本臨床社, 709 - 710
  • 別冊 日本臨床 領域別症候群シリーズ No. 33 先天異常症候群辞典, Apr. 2001, 日本臨床社, 543 - 544
  • 別冊 日本臨床 領域別症候群シリーズ No. 34 先天異常症候群辞典, Apr. 2001, 日本臨床社, 711 - 712
  • 別冊 日本臨床 領域別症候群シリーズ No. 30 神経症候群Ｖ, Apr. 2000, 日本臨床社, 353 - 354
  • 別冊 日本臨床 領域別症候群シリーズ No. 30 神経症候群Ｖ, Apr. 2000, 日本臨床社　, 23 - 25
  • 別冊 日本臨床 領域別症候群シリーズ No. 30 神経症候群Ｖ, Apr. 2000, 日本臨床社, 21 - 22
  • 小児科研修医ノート, Apr. 1999, 診断と治療社　, 103 - 104
  • The Developing Brain and its Disorders, Apr. 1984, University of Tokyo Press (Tokyo), 161 - 175
  • Mapping genes onto brain structures, Apr. 2012, YouTube　rikenchannel
  • ヒト超速進化RNAと脳機能, Apr. 2008, 実験医学, 1586 - 1587
  • 優性遺伝形式をとる神経難病（特集・小児科医のための遺伝学）, Apr. 2008, 小児内科, 1289 - 1296
  • 脳におけるアダプタータンパクIRSｐ53の細胞機能, Apr. 2004, 生体の科学　
  • 環境刺激による perturbation, Apr. 2004, 蛋白・核酸・酵素　
  • 転写制御因子の発現動態（in situ hybridization）, Apr. 2004, 蛋白・核酸・酵素　
  • The biochemistry and clinical features of galactosialidosis（査読付）, Apr. 1994, Biochim. Biophys. Acta, 244 - 254
  • 1999
  • The Developing Brain and its Disorders, 1984, Suzuki Y, Sakuraba H, Yamanaka T, Ko YM, Okamura Y, Hoogeveen T. , University of Tokyo Press

Conference Activities & Talks

  • 2D/3D image integration on the BAH viewer, Nov. 2018, Yuko Okamura-Oho, Daisuke Miyamoto, Hidetoshi Ikeno, Masahiko Morita, Hideo Yokota, Shuhei Wemler, Akira Sato, Teiichi Furuichi, Yoshihiro Okumura, Yoko Yamaguchi, San Diego, USA
  • Differential and tissue-specific gene expression in the mouse brain, Nov. 2017, Yuko Okamura-Oho, AINI (Advances in Neuroinformatics) 2017, Wako, Japan
  • Ex-vivo transcriptomic analysis on the web: a new platform of ViBrism DB for gene expression mapping and analysis, Sep. 2016, Yuko Okamura-Oho, Masahiko Morita, Kazuro Shimokawa, Masaomi Nishimura, Takahiro Tawara, Hideo Yokota, NI (Neuroinformatics) 2016, Reading, England
  • ViBrism DB Platform, May 2016, Yuko Okamura-Oho, Masahiko Morita, Masaomi Nishimura, Takahiro Tawara, Shuhei Wemler, Kazuro shimokawa, Hideo Yokota, AINI2016 and INCF Nodes Workshop, Wako, Japan
  • 3次元Ex Vivo 空間での遺伝子発現分布の測定 TT法で全脳を網羅解析, Jan. 2016, 於保 祐子, nano tech 2016（国際ナノテクノロジー総合展・技術会議） 理研ブース
  • Integration of anatomical and topological maps for functional analysis of the brain, Nov. 2015, 於保　祐子, AINI2015 in Tokyo, Japan
  • Ex-vivo transcriptomic analysis on the web: a new platform of ViBrism DB for gene expression mapping and analysis, Aug. 2015, Yuko Okamura-Oho, Masahiko Morita, Kazuro Shimokawa, Masaomi Nishimura, Takahiro Tawara, Hideo Yokota, NI(Neuroinformatics)2015, Demo session: in Cairns
  • トランスクリプトーム トモグラフィー： 遺伝子発現を脳３次元空間にマップする, Feb. 2015, 於保　祐子, RIKENシンポジウム「3次元内部構造顕微鏡による3次元計測の生物・材料分野への挑戦と展開」
  • Transcriptome tomography: mapping genes onto 3D brain structures, Nov. 2014, Yuko Okamura-Oho, Kazuro Shimokawa, Sakiko Nakamura, Yuki Tsujimura, Masaomi Nishimura, Satoko Takemoto, Masahiko Morita, Takashi Ijiri, Takehiro Tawara, Hideo Yokota, Annual meeting of Society of Neuroscience 2014, in Washington DC
  • ViBrism Database: a Platform for analysis of Expression Maps and Co-Expression Networks, Sep. 2014, Yuko Okamura-Oho, Masahiko Morita, Hideo Yokota, Shinji Kondo, Kazuro Shimokawa, Satoshi Oota, Teiichi Furuichi , Yoko Yamaguchi, AINI2014 Poster session in Wako
  • Integrated Analysis of Expression Maps and Co-Expression Networks Using a Dataset of ViBrism DB, Sep. 2014, Yuko Okamura-Oho, Kazuro Shimokawa, Masaomi Nishimura, Satoko Takemoto, Masahiko Morita, Hideo Yokota, AINI2014 in Wako
  • Novel genes located in the co-expression networks detected with Transcriptome Tomography, Aug. 2014, Yuko Okamura-Oho, Kazuro Shimokawa, Masaomi Nishimura, Satoko Takemoto, Akira Sato, Teiichi Furuichi, Hideo Yokota, NI(Neuroinformatics)2014, Poster session: in Leiden
  • 「トランスクリプトーム・トモグラフィーを用いた遺伝子発現に基づく全脳地図作成」, Jun. 2014, 於保　祐子, 科学技術振興機構主催　理化学研究所新技術説明会
  • ViBrism-DBデータセットを用いた遺伝子発現地図と共発現ネットワークの統合解析で明らかになった発生学的に保存された脳の意匠, Dec. 2013, 於保祐子、下川和郎、竹本智子、横田秀夫, 第３６回日本分子生物学会年会
  • Developmentally conserved brain designs quantifiable with Transcriptome Tomography, Aug. 2013, Yuko Okamura-Oho, Kazuro Shimokawa, Satoko Takemoto, Hideo Yokota, NI (Neuroinformatics)2013, Stockholm
  • Integrated Analysis of Anatomical Gene Expression Maps and Co-Expression Networks Using a Database, ViBrism, Sep. 2012, Yuko Okamura-Oho, Kazuro Shimokawa, Satoko Takemoto, Gang Song, James Gee, Hideo Yokota, NI (Neuroinformatics)2012, in Munich
  • Integrated Analysis of Anatomical Gene Expression Maps and Co-Expression Networks Using a Database, ViBrism, Sep. 2012, 於保　祐子, NeuroInformatics2012 総会
  • A Use Case of Transcriptome Analysis Frameworks in the Web-Accessible Anatomical Space of the Mouse Brain, May 2012, 於保　祐子, MRC/INCF/SICSA 合同「アトラスインフォマティクスワークショップ」
  • 遺伝子発現脳図譜ViBrism のWaxholm標準脳空間への統合　, Dec. 2011, 於保祐子、西村正臣、竹本智子、横田秀夫、Gang Song, and James Gee, 第３４回日本分子生物学会年会
  • Integration of 3D gene expression maps of ViBrism-DB into the standard coordinate Waxholm Space, Sep. 2011, Yuko Okamura-Oho, Masaomi Nishimura, Satoko Takemoto, Hideo Yokota, Gang Song, and James Gee, NI (Neuroinformatics)2011, Poster session: in Boston
  • 定量的3次元遺伝子発現データに基づいたマウス脳アトラスの作成とその解析, Dec. 2010, 於保祐子、竹本智子、横田秀夫, 日本分子生物学会年会
  • ViBrism: a Database for Gene Expression 3D-maps of the Virtual Mouse Brain Produced with New Sampling Technology(Demo session), Sep. 2010, Yuko Okamura-Oho, Kazuro Shimokawa, Satoko Takemoto, Hideo Yokota, NI (Neuroinformatics)2010 in Kobe
  • 3D-Analysis of Comprehensive Gene Expression Profiling in the Virtual Brain, Jan. 2010, 於保　祐子, 理化学研究所　理論生物学セミナー
  • Development of 3D-Analysis System for Comprehensive Gene Expression Profiling in the Virtual Brain, Dec. 2009, 於保　祐子, 日本分子生物学会第32回年会シンポジウム
  • 遺伝性神経疾患責任遺伝子のマウス脳での3次元発現解析, Sep. 2009, 於保祐子、中村佐紀子、横田秀夫, 日本人類遺伝学会第54回大会
  • 3D-ISM を用いた遺伝子発現の仮想ボクセル解析, Dec. 2008, 於保祐子、下川和郎、中村佐紀子、姫野龍太郎、横田秀夫, 日本分子生物学会年会
  • The New Phase of Transcriptome Analysis　, Mar. 2007, 於保　祐子, IISc-RIKEN 合同カンファレンス「ゲノミクスとバイオインフォマティクス」
  • 形状情報を伴った遺伝子発現情報取得の重要性, Nov. 2006, 於保　祐子, 理研シンポジウム「生体形状情報の数値化及びデータベース構築研究」
  • DRPLA蛋白の翻訳後修飾, Dec. 2002, 於保祐子, 山崎麻由, 宮下俊之, 山田正夫, 第25回日本分子生物学会年会
  • DRPLA蛋白に結合能を持つインスリン／IGF-I受容体基質IRSp53のゲノム構造とスプライシング, Nov. 2002, 於保祐子, 宮原篤, 宮下俊之,, 日本人類遺伝学会第47回大会
  • DRPLA蛋白の機能ドメイン解析, Dec. 2001, 於保祐子，中村真耶，宮下俊之，山田正夫, 第24回日本分子生物学会年会　
  • DRPLA蛋白に結合能を持つinsulin/IGF-I受容体基質IRSp53の機能, Oct. 2001, 於保祐子，中村真耶，宮下俊之，山田正夫, 日本人類遺伝学会第46回大会
  • 53kDaインスリン受容体基質（IRSp53）の機能, Dec. 2000, 於保祐子，緒方幸恵，宮下俊之，山田正夫, 第23回日本分子生物学会年会　
  • DRPLA蛋白の機能ドメイン, Oct. 2000, 於保祐子，緒方幸恵，宮下俊之，山田正夫, 日本人類遺伝学会第45回大会
  • 53kDaインスリン受容体基質（IRSp53）のインスリン刺激による細胞膜近傍への移行, Dec. 1999, 於保祐子，嶋誠悟，宮下俊之，山田正夫, 第22回日本分子生物学会年会
  • DPRLA蛋白はインスリン／IGF-Iシグナル伝達機構に関与する, Dec. 1998, 於保祐子、宮下俊之、山田正夫, 第21回日本分子生物学会年会
  • DRPLA蛋白に結合し、細胞内シグナル伝達に関わる遺伝子産物の解析, Oct. 1998, 於保祐子、宮下俊之、山田正夫, 日本人類遺伝学会第43回大会
  • DRPLA蛋白質に結合能を持つ、受容体型チロシンキナーゼ基質様遺伝子の単離, Oct. 1997, 於保祐子, 長尾芳朗, 宮下俊之,, 日本人類遺伝学会第42回大会
  • Integrated Analysis of Anatomical Gene Expression Maps and Co-Expression Networks Using a Database, ViBrism, 11 Sep. 2012, Okamura-Oho Yuko, Neuroinformatics2012
  • A Use Case of Transcriptome Analysis Frameworks in the Web-Accessible Anatomical Space of the Mouse Brain, 15 May 2012, Okamura-Oho Yuko, Joint MRC/INCF/SICSA Workshop on Atlas Informatics
  • Development of 3D-Analysis System for Comprehensive Gene Expression Profiling in the Virtual Brain, 09 Dec. 2009, Okamura-Oho Yuko
  • The New Phase of Transcriptome Analysis, 15 Mar. 2007, Okamura-Oho Yuko, IISc-RIKEN Conference on Genomics and Bioinformatics

Patents

  • Method of constructing gene expression image and system for constructing gene expression image, Hideo Yokota, Yuko Oho, Kazurou Shimokawa
  • Method of constructing gene expression image and system for constructing gene expression image, Hideo Yokota, Yuko Oho, Kazurou Shimokawa

Researcher Profile and Settings

Academic association activities

  • Society of Neuroscience
  • Neuroinformatics Coordinating Facility (INCF)
  • THE JAPAN SOCIETY OF HUMAN GENETICS
  • THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
  • THE JAPANESE SOCIETY OF CHILD NEUROLOGY
  • JAPAN PEDIATRIC SOCIETY

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